A 38-year-old woman with gastrinoma and multiple lipomas is started on a proton pump inhibitor. Which laboratory value should be monitored due to associated hyperparathyroidism in this syndrome?

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Multiple Choice

A 38-year-old woman with gastrinoma and multiple lipomas is started on a proton pump inhibitor. Which laboratory value should be monitored due to associated hyperparathyroidism in this syndrome?

Explanation:
This is MEN1 (parathyroid, pancreatic, and pituitary tumors). The parathyroids are commonly affected in MEN1, leading to hyperparathyroidism and hypercalcemia. Monitoring calcium is essential because it reflects parathyroid disease activity and guides management, including potential surgical intervention. While gastrinoma activity is tracked by gastrin levels and pituitary issues by prolactin or TSH, the question specifically asks about the associated hyperparathyroidism, so calcium is the relevant lab to monitor.

This is MEN1 (parathyroid, pancreatic, and pituitary tumors). The parathyroids are commonly affected in MEN1, leading to hyperparathyroidism and hypercalcemia. Monitoring calcium is essential because it reflects parathyroid disease activity and guides management, including potential surgical intervention. While gastrinoma activity is tracked by gastrin levels and pituitary issues by prolactin or TSH, the question specifically asks about the associated hyperparathyroidism, so calcium is the relevant lab to monitor.

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